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Figure 5: Melanoma (a) Cell block, S-100 stain showing a positive (brown) nuclear and cytoplasmic staining, ×10. (b) Aspirate smear, Diff-Quik stain, ×20 with highly pleomorphic cells, some binucleated with prominent nucleoli. (c) Cell block, higher magnification showing characteristic prominent cherry red nucleoli

Figure 5: Melanoma (a) Cell block, S-100 stain showing a positive (brown) nuclear and cytoplasmic staining, ×10. (b) Aspirate smear, Diff-Quik stain, ×20 with highly pleomorphic cells, some binucleated with prominent nucleoli. (c) Cell block, higher magnification showing characteristic prominent cherry red nucleoli