Annals of Thoracic Medicine
LETTER TO THE EDITOR
Year
: 2011  |  Volume : 6  |  Issue : 1  |  Page : 46--47

Filarial pleural effusion


K Gowrinath 
 Department of Pulmonary Medicine, Narayana Medical College, Nellore-524002, India

Correspondence Address:
K Gowrinath
Department of Pulmonary Medicine, Narayana Medical College, Nellore-524002
India




How to cite this article:
Gowrinath K. Filarial pleural effusion.Ann Thorac Med 2011;6:46-47


How to cite this URL:
Gowrinath K. Filarial pleural effusion. Ann Thorac Med [serial online] 2011 [cited 2022 Jan 27 ];6:46-47
Available from: https://www.thoracicmedicine.org/text.asp?2011/6/1/46/74279


Full Text

Sir,

I read the article of Garg, et al. [1] with great interest. As a co-author of our work [2] cited in their article, I would like to make it clear that the microfilariae detected in the pleural biopsy material of our case were of Wuchereria bancrofti and not Mansonella perstans as quoted in the text by the authors. I was surprised to note that the closed pleural biopsy was not carried out as there was a chance to establish the filarial etiology within the pleura. Microfilariae reside in the arterioles of pulmonary system during daytime and appear in peripheral blood and other body fluids only in the night time during the peak biting time of mosquito vectors. The traditional diagnostic method of filariasis is to demonstrate microfilariae microscopically in the peripheral blood (capillary finger prick or thick venous blood smears) drawn in the night or presence of circulating filarial antigen. [3] Filariasis is a major health problem in India and microfilariae have been detected along with other diseases such as tuberculosis, non-Hodgkin's disease, etc. [4] I am curious to know the scientific basis regarding the number of times a clinical specimen like pleural fluid can be tested and methodology adapted by the authors who successfully demonstrated microfilariae on all four occasions to conclude that the pleural effusion was due to filariasis only.

References

1Garg R, Sodhi R, Jabeed P, Rastogi A. Non-resolving pleural effusion in an elderly woman: A case report. Ann Thorac Med 2010;5:247-8.
2Arora VK, Gowrinath K. Pleural effusion due to lymphatic filariasis. Indian J Chest Dis Allied Sci 1994;36:159-61.
3Rosenblatt JE. Laboratory diagnosis of infections due to blood and tissue parasites. Clin Infect Dis 2009;49:1103-9.
4Gupta K, Sehgal A, Puri MM, Sidhwa HK. Microfilariae in association with other diseases. A report of six cases. Acta Cytol 2002;46:776-8.