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Figure 2 :Nitrotyrosine formation in the lung. NO reaction with superoxide generates peroxynitrite (ONOO-) (reaction A). Peroxynitrite and CO2 form an adduct that has enhanced nitrating capabilities (reaction B). In the absence of target molecules, NO3- forms. NO2- formation is relatively slow and may be consumed by peroxidase catalyzed reaction C to generate nitrotyrosine (Tyr-NO2) also

Figure 2 :Nitrotyrosine formation in the lung. NO reaction with superoxide generates peroxynitrite (ONOO-) (reaction A). Peroxynitrite and CO2 form an adduct that has enhanced nitrating capabilities (reaction B). In the absence of target molecules, NO3- forms. NO2- formation is relatively slow and may be consumed by peroxidase catalyzed reaction C to generate nitrotyrosine (Tyr-NO2) also