Annals of Thoracic Medicine
CASE REPORT
Year
: 2014  |  Volume : 9  |  Issue : 1  |  Page : 39--41

A rare case of alpha 1-antitrypsin deficiency associated with hypogammaglobulinemia and recurrent pulmonary thrombosis


Raghav Gupta1, Srilekha Sridhara1, John A Wood2 
1 Department of Internal Medicine, Allergy and Immunology, St. Luke's Hospital, Chesterfield, MO, USA
2 Department of Pulmonology, Allergy and Immunology, St. Luke's Hospital, Chesterfield, MO, USA

Correspondence Address:
Raghav Gupta
14463, Greencastle Drive, Apt#6, Chesterfield, MO 63017
USA

Alpha 1-antitrypsin (AAT) belongs to the family of serpins (serine protease inhibitors). Loop sheet polymerization is the pathology behind serpinopathies which encompasses AAT, anti-thrombin III and neuroserpin deficiency. To the best of our knowledge, we report the first case of alpha 1-antitrypsin deficiency associated with hypogammaglobulinemia and recurrent pulmonary thrombosis without any concomitant use of drugs.


How to cite this article:
Gupta R, Sridhara S, Wood JA. A rare case of alpha 1-antitrypsin deficiency associated with hypogammaglobulinemia and recurrent pulmonary thrombosis.Ann Thorac Med 2014;9:39-41


How to cite this URL:
Gupta R, Sridhara S, Wood JA. A rare case of alpha 1-antitrypsin deficiency associated with hypogammaglobulinemia and recurrent pulmonary thrombosis. Ann Thorac Med [serial online] 2014 [cited 2020 Feb 22 ];9:39-41
Available from: http://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2014;volume=9;issue=1;spage=39;epage=41;aulast=Gupta;type=0