A preliminary clinico-epidemiological portrayal of COVID-19 pandemic at a premier medical institution of North India
Sudhir Bhandari1, Ajit Singh Shaktawat1, Raman Sharma1, Amitabh Dube2, Shivankan Kakkar3, S Banerjee1, Prakash Keshwani1, Shrikant Sharma1, Sunil Mahavar1, CL Nawal1, Sudhir Mehta1, Abhishek Agarwal1, Vishal Gupta1, Ashwin Mathur1, Amita Kashyap4, AS Dua4, Dilip Raj4, Kapil Gupta2, Jitendra Kumar Gupta2, Neeraj Verma5, Amit Tak2
1 Department of Medicine, SMS Medical College Hospital, Jaipur, Rajasthan, India
2 Department of Physiology, SMS Medical College Hospital, Jaipur, Rajasthan, India
3 Department of Pharmacology, SMS Medical College Hospital, Jaipur, Rajasthan, India
4 Department of Community Medicine, SMS Medical College Hospital, Jaipur, Rajasthan, India
5 Department of Pathology, SMS Medical College Hospital, Jaipur, Rajasthan, India
Dr. Shivankan Kakkar
Department of Pharmacology, SMS Medical College Hospital, Jaipur, Rajasthan
CONTEXT: The outbreak and spread of severe acute respiratory syndrome coronavirus 2 has led to a global exigency of colossal and monstrous proportions in terms of public health and economic crisis. Till date, no pharmaceutical agent is known to manage in terms of prevention and treatment of coronavirus disease 2019 (COVID-19), the disease caused by a novel virus.
AIMS: The aim of the present work was to understand the underlying disease profile and dynamics that could provide relevant inputs and insight into pathophysiology and prevent further spread and evolve management strategies of COVID-19 patients from data-driven techniques.
SETTINGS AND DESIGN: A retrospective observational descriptive study was conducted on 29 COVID-19 patients admitted at a premier medical institution of North India in the months of February and March 2020.
METHODS: The patients were diagnosed with reverse transcription-polymerase chain reaction test. Demographic, clinical, and laboratory data were collected.
RESULTS: The mean age of population was 38.8 years with male preponderance, of which two patients were residents of Italy, and others hailed from semi-arid and Western sandy arid regions of Rajasthan (urban population). The major presenting symptom complex of said COVID-19 sample population included fever (48%), cough (31%), and shortness of breath (17%). Most of the patients (83%) had no comorbidity. No clinical correlation (r) could be appreciated between the duration of test positivity and age of afflicted COVID-19 patients (r = −0.0976).
CONCLUSIONS: The present evaluation of various facets of the ongoing global pandemic of COVID-19 is an attempt to portray early clinical and epidemiological parameters of the menace of COVID-19 patients admitted at SMS Medical College and Attached Hospitals, Jaipur.