Annals of Thoracic Medicine Official publication of the Saudi Thoracic Society, affiliated to King Saud University
 
Search Ahead of print Current Issue Archives Instructions Subscribe e-Alerts Login 
Home Email this article link Print this article Bookmark this page Decrease font size Default font size Increase font size
REVIEW ARTICLE
Year : 2019  |  Volume : 14  |  Issue : 3  |  Page : 173-178

Prevalence of the epidermal growth factor receptor mutations in lung adenocarcinoma patients from the Middle East region


Department of Internal Medicine, Division of Hematology and Oncology, American University of Beirut, Beirut, Lebanon

Correspondence Address:
Dr. Arafat Hussein Tfayli
American University of Beirut Medical Center, Naef K. Basile Cancer Institute, 11-0236, Riad El Solh, 1107 2020, Beirut
Lebanon
Login to access the Email id


DOI: 10.4103/atm.ATM_344_18

Rights and Permissions

Lung cancer remains a major cause of cancer mortality with a 5-year survival in advanced stages around 4%. Platinum-based chemotherapy was routinely used as the standard of care in patients with advanced nonsmall cell lung cancer, but it is being progressively replaced by targeted molecular therapy. One of the molecular aberrations harbored by lung adenocarcinoma is the epidermal growth factor receptor (EGFR). A large ethnic variation has been reported in the prevalence of EGFR mutations in patients with lung adenocarcinoma. Data regarding its prevalence from the Middle East area remains limited. This paper aims at reviewing the data available for the prevalence of this mutation in the Middle Eastern patient population and comparing it with other reported series.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed449    
    Printed26    
    Emailed0    
    PDF Downloaded79    
    Comments [Add]    

Recommend this journal