Annals of Thoracic Medicine Official publication of the Saudi Thoracic Society, affiliated to King Saud University
 
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CASE REPORT
Year : 2011  |  Volume : 6  |  Issue : 3  |  Page : 149-151

Massive hemothorax following administration of intrapleural streptokinase


1 Department of Surgery, Faculty of Medicine, Universiti Kebangsaan, Kuala Lampur, Malaysia
2 Department of Internal Medicine, Faculty of Medicine, International Islamic University of Malaysia, Kuala Lampur, Malaysia

Correspondence Address:
Feng Yih Chai
Department of Surgery, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latiff, Bandar Tun Razak, 56000 Cheras, Kuala Lumpur
Malaysia
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DOI: 10.4103/1817-1737.82451

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The administration of intrapleural streptokinase (IPSK) is widely practiced in the management of loculated empyema thoracis. To our knowledge, there have been only 4 cases of hemorrhagic complications attributed to the administration of IPSK reported in the literature. In this article, we report a case of a 17-year-old girl who received IPSK and developed shock, anemia, coagulopathy and massive hemothorax. Our discussion focuses on the hemorrhagic complication of chest tube insertion and the role of IPSK in blood clot lysis and inhibition of local hemostasis.


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