Annals of Thoracic Medicine Official publication of the Saudi Thoracic Society, affiliated to King Saud University
 
Search Ahead of print Current Issue Archives Instructions Subscribe e-Alerts Login 
Home Email this article link Print this article Bookmark this page Decrease font size Default font size Increase font size


 
CASE REPORT
Year : 2010  |  Volume : 5  |  Issue : 1  |  Page : 47-49
Thoracoscopic enucleation of esophageal leiomyoma in patient with men I syndrome


1 College of Medicine, Al-Faisal University, Riyadh; Division of Thoracic Surgery, Department of Surgery, King Faisal Specialist, Hospital & Research Centre, Riyadh, Saudi Arabia
2 Division of Thoracic Surgery, Department of Surgery, King Faisal Specialist, Hospital & Research Centre, Riyadh, Saudi Arabia

Date of Submission07-Jun-2009
Date of Acceptance12-Jul-2009
Date of Web Publication15-Jan-2010

Correspondence Address:
Waleed N Saleh
Division of Thoracic Surgery, Department of Surgery, P. O. Box 3354, Riyadh 11211, MBC - 40
Saudi Arabia
Login to access the Email id


DOI: 10.4103/1817-1737.58960

PMID: 20351961

Rights and Permissions

   Abstract 

Minimal invasive thoracic surgery is growing rapidly and may become the standard of care for certain diseases. Its benefits over traditional surgery, including reduced morbidities and hospital stay, have been well established in several reports. We herein report a case of midesophageal leiomyoma in a patient with MEN I syndrome successfully enucleated by thoracoscopy highlighting the technical details of the procedure.


Keywords: Enucleation, leiomyoma, thoracosocpy


How to cite this article:
Saleh WN, Bamosa A, Al-Mutairi H, Al-Kattan KM. Thoracoscopic enucleation of esophageal leiomyoma in patient with men I syndrome. Ann Thorac Med 2010;5:47-9

How to cite this URL:
Saleh WN, Bamosa A, Al-Mutairi H, Al-Kattan KM. Thoracoscopic enucleation of esophageal leiomyoma in patient with men I syndrome. Ann Thorac Med [serial online] 2010 [cited 2020 Apr 1];5:47-9. Available from: http://www.thoracicmedicine.org/text.asp?2010/5/1/47/58960


Benign tumors of the esophagus constitute less than 10% of all esophageal neoplasm, [1] the commonest of which is leiomyoma which accounts for about two thirds of all benign tumors of the esophagus. [2] On the other hand 10% of gastrointestinal leiomyomas are located in the esophagus and around 90% of cases occur between the ages of 20 and 69 with the male to female ratio of approximately 2:1. [3] The commonest location is the lower esophagus (56%) followed by the middle (33%). [2]

Leiomyomas usually present as single lesion and one-half of the cases are smaller than five cm in greatest dimension. It may remain asymptomatic, but when symptoms arise they are usually in the form of dysphagia, pain and weight loss. The preferred methods for diagnosis are barium swallow and endoscopy. In barium swallow the lesion appears as a smooth rounded filling defect with sharp demarcation [4] and on endoscopy the tumor is freely mobile with intact overlying mucosa, biopsy should be avoided due to the potential risks of bleeding, perforation, and infection. Biopsy may also complicate subsequent enucleation.

We herein present the first case of thoracoscopic excision of esophageal leiomyoma in Saudi Arabia.


   Case Report Top


A 32-year-old Saudi male patient who is a known case of Multiple Endocrine Neoplasia type 1 (MEN1) status post parathyroidectomy, distal panreatectomy and spleenectomy in 2006 was found, on CT screening, to have extra luminal midesophageal mass about five cm in greatest dimension at the level of the carina, compatible with leiomyoma [Figure 1]. Further review of symptoms revealed mild intermittent dysphagia for solids. Based on these findings the decision was to proceed with thoracoscopic enucleation for which the patient agreed and was consented.

Under general anesthesia utilizing a double lumen tube and in left lateral position, right thoracoscopy was performed after right lung isolation using four ports: 11-mm port is inserted through the sixth intercostal space by blunt dissection at the midaxillary line to provide access for a 10-mm thoracoscope. Three more ports are placed bluntly to provide access for surgery: Five mm port is placed in the posterior axillary line at the fifth intercostal space, 10 mm scope 30 degree is placed in the posterior axillary line at the eighth intercostals space, and a five- mm trocar is placed in the anterior axillary line at the ninth intercostals space for lung retraction.

The mediastinal pleura over the esophagus were divided to expose the tumor and the adjacent esophagus. About five-cm of the esophagus below the azygus vein was mobilized and the tumor was located. A four-cm myotomy was performed using combination of hook and endoscopic scissor avoiding injury to the mucosa. After that blunt dissection was performed separating the tumor from the mucosa, followed by applying traction suture to the tumor to aid in tumor elevation as well as in the dissection which was done mostly by blunt dissection and occasionally using sharp dissection. After tumor enucleation, the specimen was placed in a retrieval bag introduced through anterior 10- mm trocar and was delivered through this trocar wound [Figure 2].

To ensure that the underlying mucosa is intact, the right thoracic cavity was instilled with normal saline. Size 14F nasogastric tube was inserted proximal to the area of the myotomy and 50-cc of air injected by the anesthetist gently which did not show any leak. The esophageal muscle fibers were approximated using interrupted 2-0 absorbable suture. Size 24F chest tube was introduced through the anterior 10-mm port and directed towards the apex, the trocars were removed under vision, the intercostal muscle fibers were approximated with 2-0 absorbable suture and the skin closed in subcuticular pattern.

The patient was kept nil by mouth till next day when contrast swallow confirmed mucosal integrity, after which he was started on oral fluid sand his drain was removed. On the second postoperative day he was on a soft diet and discharged on the same day. He was to be on soft diet for two weeks. Final histology confirmed the diagnosis of leiomyoma.


   Discussion Top


Review of literature showed no reports of simultaneous occurrence of MEN syndrome and gastrointestinal leiomyomas. We think this was an incidental finding rather than true association.

Surgical excision of esophageal leiomyoma is advised for symptomatic cases and for asymptomatic cases if the tumor is larger than five cm, if the tumor is increasing in size and if there is mucosal ulceration. [5],[6] Esophageal resection is indicated for large lesion (greater than eight cm), if the tumor is densely adherent to the mucosa, or if the there was extensive damage to the mucosa during the dissection that precludes safe repair. [2],[7]

Right thoracotomy is the most common procedure used for excision of midesophageal leiomyoma, while distal third lesions are classically approached through left thoracotomy. Upper midline laparotomy may also be used for tumors near the gastro esophageal junction. Muscle fibers are gently separated and the tumor is enucleated by blunt dissection. There is general agreement on approximation of muscle fibers after enucleation to prevent the formation of pseudo diverticulum; [8] however this approximation should be done loosely to avoid decreasing the propulsive activity of the esophageal body. The reported mortality from thoracotomy for leiomyoma excision ranged from 0 to 1.3%; [2] in addition to the well known morbidities of thoracotomy which includes pain, atelectasis, pneumonia and slightly prolonged hospital stay.

This approach has been increasingly used after Everitt reported the first successful thoracoscopic enucleation for esophageal leiomyoma in 1992. [9] A right thoracoscopy is used for proximal two-third lesions and left thoracoscopy for distal-third tumors.

Peroperative endoscopy is an important adjunct to the surgery. It helps in locating the tumor, ensuring complete tumor excision and integrity of the esophageal mucosa. Unfortunately we could not use it in our case.

A review of literature on thoracoscopic excision of leiomyoma found the outcome excellent with majority reporting complete resolution of symptoms. There was no mortality but morbidities included mucosal tear (13.3%), postoperative mucosal bulging (10%) and pleural effusion (3.3%). [8],[10] It offers several advantages over thoracotomy including: Less surgical trauma and pain, minimal effect on respiratory mechanics, shorter hospital stay as well as better cosmesis.

Although some surgeons do not routinely perform contrast swallow postoperatively, we prefer to do it in order to ensure mucosal integrity as well as the adequacy of contrast flow at the enucleation site.


   Conclusion Top


Thoracoscopic enucleation for esophageal leiomyoma is safe and feasible. It should be the procedure of choice for lesions less than five cm since it is less invasive and provides shorter recovery with same functional result to thoracotomy.


   Acknowledgments Top


The authors would like to acknowledge Dr. Lina Asaad, Department of Pathology at King Faisal Specialist Hospital for the provision of the pathology slide.

 
   References Top

1.Postlethwait RW, Lowe JE. Benign tumors and cysts of the esophagus. In: Orringer MB, Zuidema GD, editors. Shackelford's surgery of the alimentary tract. Philadelphia, PA: WB Saunders; 1996. p. 369-86.   Back to cited text no. 1      
2.Seremetis MG, Lyons WS, deGuzman VC, Peabody JW Jr. Leiomyomata of the esophagus. An analysis of 838 cases. Cancer 1976;38:2166-77.   Back to cited text no. 2      
3.Bonavina L, Segalin A, Rosati R, Pavanello M, Peracchia A. Surgical therapy of esophageal leiomyoma. J Am Coll Surg 1995;181:257-62.   Back to cited text no. 3  [PUBMED]  [FULLTEXT]  
4.Yang PS, Lee KS, Lee SJ, Kim TS, Choo IW, Shim YM, et al. Esophageal leiomyoma: Radiologic findings in 12 patients. Korean J Radiol 2001;2:132-37.   Back to cited text no. 4  [PUBMED]  [FULLTEXT]  
5.Zuccaro G Jr, Rice TW. Tumors of the esophagus. In: Brandt LJ, editor. Clinical practice of gastroenterology. Philadelphia: Churchill Livingstone; 1999:131-34.   Back to cited text no. 5      
6.Fleischer DE, Haddad NG. Neoplasms of the esophagus. In: Castell DO, Richter JE, editors. The Esophagus. 3 rd ed. Philadelphia: Lippincott,Williams andWilkins; 1999. p. 252.   Back to cited text no. 6      
7.Hatch GF 3 rd , Wertheimer-Hatch L, Hatch KF, Davis GB, Blanchard DK, Foster RS Jr, et al. Tumors of the esophagus. World J Surg 2000;24:401-11.   Back to cited text no. 7      
8.Bonavina L, Segalin A, Rosati R, Pavanello M, Peracchia A. Surgical therapy of esophageal leiomyoma. J Am Coll Surg 1995;181:257-62.   Back to cited text no. 8      
9.Everitt NJ, Glinatsis M, McMahon MJ. Thoracoscopic enucleation of leiomyoma of the oesophagus. Br J Surg 1992;79:643.   Back to cited text no. 9  [PUBMED]  [FULLTEXT]  
10.Taniguchi E, Kamiike W, Iwase K, Nishida T, Akashi A, Ohashi S, et al. Thoracoscopic enucleation of a large leiomyoma located on the left side of the esophageal wall. Surg Endosc 1997;11:280-2.  Back to cited text no. 10  [PUBMED]  [FULLTEXT]  


    Figures

  [Figure 1], [Figure 2]

This article has been cited by
1 Complete thoracoscopic enucleation of giant leiomyoma of the esophagus: a case report and review of the literature
XiaoXing Hu,Hui Lee
Journal of Cardiothoracic Surgery. 2014; 9(1): 34
[Pubmed] | [DOI]



 

Top
Print this article  Email this article
 
  Search
 
   Next article
   Previous article 
   Table of Contents
  
    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
    Article in PDF (718 KB)
    Citation Manager
    Access Statistics
    Reader Comments
    Email Alert *
    Add to My List *
* Registration required (free)  


    Abstract
    Case Report
    Discussion
    Conclusion
    Acknowledgments
    References
    Article Figures

 Article Access Statistics
    Viewed2768    
    Printed191    
    Emailed0    
    PDF Downloaded447    
    Comments [Add]    
    Cited by others 1    

Recommend this journal