Annals of Thoracic Medicine Official publication of the Saudi Thoracic Society, affiliated to King Saud University
 
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BRIEF REVIEW
Year : 2008  |  Volume : 3  |  Issue : 3  |  Page : 100-103

Role of nitric oxide in management of acute respiratory distress syndrome


Intensive Care Unit, Department of Intensive Care Medicine, Salmaniya Medical Complex, Manama, Bahrain

Correspondence Address:
A H Akmal
Department of Intensive Care Medicine, Salmaniya Medical Complex, P.O. Box 12, Manama
Bahrain
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DOI: 10.4103/1817-1737.41914

PMID: 19561888

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The current mortality rate of patients suffering from acute respiratory distress syndrome (ARDS) is between 45% and 92%, with most dying within the first two weeks of the illness. In an effort to combat such an alarmingly high mortality rate, various treatment therapies such as low tidal volume ventilation strategies, corticosteroid therapy, and use of nitric oxide (NO) have been attempted in the management of patients with ARDS. Three cases which were admitted to the ICU and confirmed to have ARDS were unable to be weaned from ventilatory support, and nitric oxide therapy was initiated. It improved patients' oxygenation for short periods of time but did not affect the mortality. The patients could not be weaned from the ventilator and expired.


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